This study aims to investigate if eight weeks of Pilates based exercise has any influence on some blood parameters like Leucocyte (white blood cell – WBC) Red Blood Cell (RBC), Hemoglobin (HGB), hematocrit (HCT), Median Cell Volume (MCV), Median Cell Hemoglobin Concentration (MCHC), Red Cell Distribution Width (RDW), Thrombocyte (platelet - PLT), Plateletcrit (PCT), Platelet Distribution Width (PDW) and Median Corpuscular Hemoglobin (Median Hemoglobin Volume, MCH), in addition to the direction and strength of any influence present. With this aim, 16 volunteering women with an age average of 30,81 ± 9,44 years were included in the study. The participants’ fasting blood samples were collected in a medical facility before the planned exercise program was commenced. After the completion of the three days a week exercise program that lasted for eight weeks, the participants’ blood samples were collected once more under the same conditions. The data collected from these samples were evaluated with SPSS 23 package software using bivariate and paired-samples t-test. The results indicate that there are no statistically relevant relationships between the WBC, HCT, MCV, RDW, PLT, PCT and PDW values and the parameters of the pre and post exercise blood samples. In addition, the averages of RBC and MCH values of the samples were found to have a relationship with p<0.05, while HGB and MCHC averages were found to have a relationship with p<0.01. As a result, the exercise type applied was evaluated to have small and large influences in positive and negative directions on the investigated blood parameters.